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About the Speaker


Assoc Prof Michael L. “Luke” JAMES​


MD, Department of Anesthesiology,

Duke University 


Speaker, Neuroscience Symposium I, 22 Sep 2018


Following residencies in neurology and anaesthesiology with fellowships in neurocritical care, neuroanaesthesia, and vascular neurology, Assoc Prof James joined the faculty in the Department of Anaesthesiology at Duke University. Initially, through the benefit of a National Institutes of Health training grant award and subsequent mentored funding from the American Heart Association in the Multidisciplinary Neuroprotection Laboratories, his early research focused on pursuit of translatable mechanisms of modifying neuro-inflammation after intracerebral hemorrhage to improve long-term functional recovery. In addition, Assoc Prof James has used preclinical models of brain injury to evaluate the potential of several novel therapeutics for translation into human clinical trials, allowing his group to propel ideas from the lab to the patient bedside, and the ability to reverse translate ideas from the patient bedside back into the lab. Now as part of the Translational Acute Brain Injury Research Center and the Duke Clinical Research Institute at Duke University, Assoc Prof James is the Principal Investigator for several large, multi-centre ICH trials funded by the National Institutes of Health and industry partners. Through these roles, his research teams continue to advance translatable therapeutic opportunities into human investigation for acute ICH. Specifically, their research in ICH focuses on non-invasive measurement of brain temperature and metabolism, systemic effects of acute neurological injury, and neurological effects of gonadal hormone production and modulation.