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This is a rare opportunity, where in the same room, you might have busy clinicians and academic leaders. You actually start to understand how this all works together - and that's where you get the excitement, where there's understanding that bringing academic medicine to a busy clinical setting ultimately really distinguishes the healthcare delivery.                 








Prof Mary Klotman  
Dean, Duke University School of Medicine, USA


Programme >

Neuroscience and Behavioral Disorders Symposium
Biomarkers in Neurocognitive Diseases: Interplay between Basic Science and Clinical Research

 Track type: Symposium

Date: 17 Sep 2021


 Time: 1400 - 1530

Location: Seminar Room 2

Biomarkers are biological measures that examine normal biological processes, pathogenic processes or pharmacologic responses to a therapeutic intervention. In the field of neurocognitive disorders, such as Alzheimer’s disease (AD) and vascular dementia (VaD), biomarkers have become increasingly important to understanding the biology of these diseases. While neuroimaging and cerebrospinal fluid are the most well-known biomarkers in AD and VaD, blood-based biomarkers have recently emerged as an important biomarker with great potential. In addition, genes may play a key role in the pathophysiology of neurocognitive diseases and progress in genetic studies have uncovered various susceptibility genes.

The development of biomarkers in neurocognitive disease, which involves a multistep process, relies on various methodologies such as neuroimaging, biochemical techniques and omics technologies in different biofluids. This involves a close collaboration between basic science studies and clinical research so as to support a successful translation from bench research to clinical utility.

In this symposium, the speakers will deliver the key roles of basic science research, clinical studies and genetics in the pathophysiology of neurocognitive diseases such as AD and VaD, focusing on the importance of collaboration between basic science studies and clinical research.


Role of Clinical Studies on the Pathophysiology of Alzheimer's Disease


Dysregulation of microRNAs in Alzheimer’s disease


Speaker: Assoc Prof Zeng Li 



Clinical Research into the Pathophysiology of Vascular Dementia


Basic Science Studies in the Pathophysiology of Vascular Dementia

Speaker: Assoc Prof Liao Ping                            



*Information is correct at time of update