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Dr Barnaby Young

Senior Consultant
National Centre for Infectious Disease

Dr Barnaby is an infectious diseases consultant at NCID/TTSH where he is also head of the Singapore Infectious Diseases Clinical Research Network (SCRN). Over the COVID-19 pandemic he has been principal investigator for several large clinical studies. This includes observational studies of infection and vaccination (PROTECT and SCOPE respectively) and the clinical trials ACTIV-3/TICO which is an adaptive platform trial focusing on therapeutic monoclonal antibodies for COVID-19 and PRIBIVAC a heterologous COVID-19 booster vaccination. He is also a member of the DSRB Domain E board.

Panel Discussion

Emerging COVID-19 Hot Topic: Special Review for COVID-19

The COVID-19 pandemic is an unprecedented global challenge requiring intensive commitment of healthcare resources, public health interventions, private investment and geopolitical coordination. A central pillar to combatting the pandemic has been rapid research and development into diagnostic, therapeutic and prophylactic tools for COVID-19. This urgency has not meant that ethical standards for research should fall or be set aside, but rather that the processes for ethical review of research must be accelerated and streamlined to whatever extent feasible.

In this context, healthcare institutions in Singapore adapted existing ethics review structures to create a new domain-specific IRB specifically to review COVID-19 related studies in a rapid manner. This panel discussion will summarize this special review process, reflecting on what was achieved, challenges emerged along the way, and lessons for the future of ethics review – both for potential global health emergencies, as well as more routine biomedical research.

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